Hyperostosis Frontalis Interna


Hyperostosis frontalis interna (HFI) is a benign normal
variant of unknown cause characterized by increased
thickness of the trabecular bone of the inner vault of
the skull affecting the frontal bone. HFI is a progressive
and symmetrical process. It has an incidence of
4–5% in the general population. HFI affects women
more than men (up to 40% of cases are seen in postmenopausal
women).
Patients with HFI may suffer from headache and
neuropsychiatric diseases like epilepsy and dementia.
Additionally, HFI has been linked to various endocrinopathies
such as diabetes mellitus, toxic goiter, and
acromegaly.
Morgagni syndrome: a syndrome characterized by
obesity, hirsutism (abnormally excessive hair growth),
and HFI.


A lateral plain radiograph of the skull shows increased
bone thickness in the inner surface of the frontal bone (arrowheads)
Signs on Plain Skull Radiographs
There is increased thickening of the inner frontal bone.
Signs on CT:


Bilateral, almost symmetrical increased thickening of the inner
surface of the frontal bone.

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