Nasal Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic systemic inflammatory
disease. The disease primarily affects the peripheral joints symmetrically.
The etiology of RA is unknown. Other common
manifestations include fatigue, malaise, and morning stiffness.
Extra-articular involvement of organs such as the skin, heart,
lungs, and eyes can be significant. Nasal septal nodules and perforation
have been reported as rare manifestations of this disease
Nasal septal perforations have been attributed
to the destructive potential of the vasculitic component of the
condition. Raynaud’s phenomenon has been described in a
subset of these patients and speculation that local vasospasm
following inspiration of cold air leading to ischemia in the nose
with the similar effect of fingertip ulcers. Treatment of the
rhinologic component relies upon control of the underlying pathology.



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